Tuesday, 24 January 2017


BUY XANAX   anxiety medication

What's Xanax?

Xanax is a benzodiazepine. Xanax affect element in the brain that may be unbalanced in persons with nerves. Xanax is used to handle or cure anxiety-disorders, shock disorder, and unease due to grief.

Xanax may also be used for reasons.   Important info

You should not use Xanax in the event that you have actually narrow-angle glaucoma, in the event that you also take itraconazole or even ketoconazole, or if you are sensitive to Xanax or similar drugs Valium and Tranxene, and Ativan, others.  

You shouldn’t take Xanax when you have:
       Narrow-angle glaucoma;
*      When you’ve  itraconazole that’s you’re still taking ketoconazole; or
*      In case you affect by to alprazolam or even to other benzodiazepines, for instance chlordiazepoxide, Tranxene, Valium, lorazepam or oxazepam.
To ensure that Xanax is safe for you, inform your physician if you have:
*      Seizures or epilepsy;
*      Kidney problem or liver illness is caused by alcoholic liver disease;
*      Symptoms of asthma or  other respiration condition;
*      open-angle glaucoma;
*      a reputation for despair or thoughts that are suicidal behavior;
*      a history of medicine or alcoholic habit; or
*      If you also make use of narcotic or opioid medicine. 

Don’t make use of Xanax when you're pregnant. This medicine could result in delivery difficulty. Your baby can grow to be dependent on also the medication. This can trigger deadly detachment symptoms in the child when it’s born. Kids formed clear-thinking by habit forming medicine can need treatment that is medicinal every week. Inform your doctor if you will be expecting or plan become pregnant. Make use of efficient birth prevention to avoid pregnancy when you're taking or using Xanax.


VALIUM vs. Xanax: Is There a Difference?


Valium and Xanax are both classified as benzodiazepines, or minor tranquilizers.
Neither drug is recommended for women who are pregnant or breast-feeding.
Drug dependency and drug withdrawal are serious concerns for people taking either drug.
Many of us feel symptoms of anxiety from time to time. For most people, these moments of nervousness don’t come along very often. For others, anxiety, and all its uncomfortable symptoms is a daily occurrence.


According to the National Institute of Mental Health, every 12 months more than 18 percent of people in the United States experience symptoms of an anxiety disorder. This ongoing anxiety can affect a person’s ability to function at home, school, and work.

Treating anxiety often involves cognitive-behavioral therapy and antidepressant medications. Benzodiazepines are another class of medications used to help curb anxiety. Two commonly prescribed benzodiazepines are Valium and Xanax. Read on to learn how these two medications compare.

Similarities and differences

Valium, known generically as diazepam, and Xanax, known generically as alprazolam, are both benzodiazepines. Benzodiazepines are categorized as minor tranquilizers. They work by helping boost the activity of gamma-aminobutyric acid (GABA). GABA is a neurotransmitter, a chemical messenger that transmits signals throughout your body. If your body doesn’t have enough GABA, you may experience anxiety or have an anxiety disorder.

Although they’re in the same drug class, there are unique differences between diazepam and alprazolam.

Sleeping Tablets without prescription

AMBIEN   is a sedative, also called a hypnotic. It affects chemicals in the brain that may be unbalanced in people with sleep problems insomnia . Misuse of this medication can result in dangerous side effects.

Insomnia has been around as long as sleep has. Some even believe that William Shakespeare was an insomniac, writing as vividly as he did about sleeplessness, tossing and turning, and sleepwalking in plays like Hamlet and Macbeth. Today, old Will has millions of fellow sufferers.

The 2007 Sleep in America Survey from the National Sleep Foundation found that 67% of women say they frequently experience a sleep problem.
The 2005 Sleep in America poll found that 35% of adults experience insomnia every night.
One option today's insomniacs have that Shakespeare didn't, of course, is the sleeping pill. Over the last 10 to 15 years, the market has been inundated with new and improved sleep medications -- ones that don’t come with the same degree of hangovers, side effects, and risk of dependency that previous sleep drugs did.

But that doesn’t mean they’re risk-free, or ideal for everyone who has problems getting a solid forty winks.

A Good Night's Sleep, Without the Hangover

The older classes of sleep medications, particularly the benzodiazepines -- think Valium and Xanax -- do more than just help you sleep. They affect how you sleep, altering your actual "sleep architecture," says Donna Arand, PhD, clinical director of the Kettering Sleep Disorders Center in Kettering, Ohio.

"They tend to decrease the amount of time spent in certain stages of sleep, particularly stages three and four (the deepest, most restful stages of sleep)," says Arand, who serves on the boards of the American Academy of Sleep Medicine and the American Insomnia Association. "People also complained of hangover effects from these medications." That's because they tend to have a longer "half-life," which is the length of time the drug stays in your body.

Non-benzodiazepine hypnotics like Ambien, Ambien CR, Rozerem, Sonata, and Lunesta, however, share key advantages over previous generations of sleep drugs:

They have a relatively short half-life, so you won't wake up groggy the next day. "There are minimal reports of 'hangover' effects with these new drugs," says Arand.
They are less likely than the older sleeping pills to cause addiction, withdrawal symptoms, or a buildup of tolerance (when you require more and more drug to have the same effect).
Why? The newer medications act only on specific receptors in your brain that are focused on sleep, while older groups of drugs have a more generalized effect on multiple brain receptors. "These new drugs are among the safest medications in medicine," says Thomas Roth, MD, Director of the Sleep Disorders and Research Center at Henry Ford Health System in Detroit.   CLICK BELOW

Xanax Side Effects long term

Xanax side effects long term

You may need a qualified medical aid and therapy during the unreasonable feeling of anxiety, fear, and insomnia. Most people experience anxiety from time to time, and this is normal. But in case of the prolonged episodes of the anxiety, some people will need antianxiety products in order to have a calm state.

The modern antianxiety product Xanax is one of the best medicines for the treatment of the prolonged episodes of the anxiety and insomnia. Xanax contains the active ingredient Alprazolam which has a sedative, anxiolytic, anticonvulsive, and myorelaxing effect.

Buy Xanax Online

Anxiety appears during the increased agitation of the central nervous system and subcortical structures of the brain. As a result of the agitation, the human has negative fantasies and experiences fear, and anxiety. In order to improve the state of the patient, it is necessary to reduce the excitement of the receptors of the brain and spinal cord, and slow down the sending of the nerve impulses through the central nerve system.

Xanax perfectly copes with its task. It stimulates benzodiazepine receptors resulting in the processes which reduce the agitation of the central nervous system.

Xanax does not increase and does not reduce the concentration of the chemical neurotransmitters like antidepressants, and does not have an antidepressant activity.

A strong and fast antianxiety action is combined with a mild soporific effect. After the first application of Xanax, patients relax, do not feel anxiety, fear, and concern; they have an emotional balance, and sleep is improved, and the period of falling asleep is reduced.

Despite a fast and intense sedative effect of Xanax, it does not block the work of the central nervous system as some analogical medicines.

Some patients taking other antianxiety products often go to a doctor with problems of the complete apathy – no emotions, fatigue, and a constant desire to sleep. They cannot do their job and personal things because the processes of the central nervous system are inhibited because of the anxiety inhibition.

Xanax effects does not cause those symptoms. It has a mild activity during the inhibition of the central nervous system, and therefore motor, vegetal, and emotional functions work well.

But one should understand that every patient has own reflex during the use of Xanax. Therefore, some patients may have a temporal feeling of fatigue, slow reactions, or sleepiness. These side effects are met during the use of Xanax but they are short and do not have a negative influence on the human activity.

As reflexes differ, an individual dosage and scheme of the treatment should be used while taking Xanax. A short-term use of Xanax will be enough for some patients in order to completely inhibit anxiety and restore the emotional balance. But do not take this medicine within a long time because the symptomatic treatment of the anxiety is more successful than the prolonged inhibition of the functions of the central nervous system.

Which drug stay longer in the body, Ativan or Valium?

According some data the average half-life for Ativan is an approximate 12 hours.  So, the most patients will eliminate 50% of the drug from their body after 12 hours of ingestion.  According to this, it could take up to 2.75 days for the drug to have been fully eliminated from the body.  Other data suggest that half-life for the drug may be slightly longer at 15.7 hours.  According to this it would take nearly 3.59 days to fully eliminate the drug from the system. But, it is important to know that lorazepam’s metabolite called lorazepam glucuronide has a longer half-life time of approximately 18 hours.  To fully eliminate lorazepam glucuronide from the body it may take longer than the lorazepam itself.  Lorazepam glucuronide will remain in your system and can be detected in your urine for more than 4 days of post-ingestion.  Factors that may have an influence on lorazepam elimination include: age, body weight, liver and kidney function, genetics, metabolic rate, urinary pH, dosage and frequency of use and other drugs used at the same time.

Valium elimination half-life is estimated within the range of 30 and 56 hours, for an average of 43 hours.  This means that on average around 43 hours is needed to clear just 50% of the final dose after Valium oral administration. So, estimated time for fully clearance of diazepam is about 9.85 days.  But, this is only the case for molecule of unmetabolized diazepam and its clearance from systemic circulation. Diazepam’s metabolites may stay much longer in the body.  The most prominent metabolite of diazepam is pharmacologically active nordiazepam or desmethyldiazepam which has a half-life within the range of 40 to 100 hours. Considering nordiazepam’s elimination half-life time on average of 70 hours it will likely take around 70 hours to eliminate %50 of the nordiazepam metabolite from your plasma.  According to these results, it can be estimated that full elimination of diazepam and nordiazepam may take up to 23 days. Many different factors may have an influence on diazepam elimination from the body such as: liver function, age, body fats, genetics, metabolic rate, formulation, dosage and frequency of use, co-administration of other drugs.

Online reviews for Ativan and Valium


What is Ativan? What is Ativan used for?

Ativan is a Brand name for a medicine that contains short-acting benzodiazepine drug named lorazepam as an active ingredient. Lorazepam works by affecting chemicals in the CNS that are known as neurotransmitters which may be unbalanced in patients who suffer from different types of anxiety disorders. Ativan’s main indications are:  anxiety disorders, insomnia caused by stress or anxiety, epilepsy and status epilepticus. Ativan is also use in surgery to cause pre surgery sedation or to sedate patients who are on mechanic ventilation, for the therapy of alcohol withdrawal, and chemotherapy that causes anticipatory nausea and vomiting.  In some cases Ativan may be used for the treatment of cocaine caused acute coronary syndrome.  Ativan is available in the form of immediate-release and sublingual tablets in doses of: 0.5 mg, 1 mg and 2 mg and in the form of solution for intramuscular or intravenous injection in concentrations of 2 mg/ml and 4 mg/ml.  FDA approved lorazepam in 1977. Ativan is originally manufactured by Valeant Pharmaceuticals. It is also available in Generic form.

What is Valium? What is Valium used for?

Valium is a Brand name for a medicine that contains long-acting benzodiazepine drug named diazepam as an active ingredient. Diazepam works by affecting chemicals in the brain known as neurotransmitters that are unbalanced in patients who suffer from different types of anxiety disorder. Valium indications are: treatment of severe anxiety disorders, short-term therapy of insomnia, premedication sedative, refractory Epilepsy, status epilepticus, anticonvulsant for muscle spasms and alcohol withdrawal. Valium is available in the form of tablet in doses of: 2, 5 and 10 mg and also as a liquid for intramuscular or intravenous injection in dose of 10 mg. FDA approved diazepam for use in 1963 under the brand name Valium of Roche drug company.

How Ativan and Valium work in the body?

Lorazepam which is the active substance of Ativan works by binding to an allosteric site on GABA-A receptors of benzodiazepine receptor in the central nervous system. By binding to this receptor sites it potentiates the inhibitory effects of GABA neurotransmitter, which then opens the chloride channel in the receptor, allowing chloride influx and causing hyperpolerization of the neuron cell.

Diazepam binds nonspecifically to benzodiazepine receptors which are responsible for sleep induction, muscle relaxation, motor coordination and memory. As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A receptors, this enhances the effects of GABA by increasing GABA affinity for the GABA receptor. After binding of GABA to its binding sites, chloride channels areopened, resulting in a hyperpolarized cell membrane thus preventing further excitation of the cell.

Differences and similarities between Ativan and Valium

Ativan and Valium are central nervous system depressants classified into the class benzodiazepines drugs. Ativan’s active ingredient is lorazepam while diazepam is active ingredient of Valium. Chemically they are similar, as they both contain benzodiazepine structure. Lorazepam’s molecular formula is C15H10Cl2N2O2 while diazepam’s is C16H13ClN2O. So, lorazepam contains 1 chloride and 1 oxygen atom more than diazepam, which theoretically means that lorazepam should be more reactive and potent drug than diazepam. 1mg dose of Lorazepam is comparable to the effect of 10mg of Diazepam. That is why lorazepam has a higher addictive potential, compared to other benzodiazepines, including diazepam.

Differences and similarities between Ativan and Valium

Both drugs works by affecting GABA neurotransmitter actions, which is a major inhibitory neurotransmitter in the brain. This causes nerve impulses to slow down, resulting in a sedating and calming effect.

Main difference between these two drugs is certainly their duration of action. Valium is known as long-acting benzodiazepine drug with half-life elimination time in the body of about 20-50 hours for diazepam and 3-100 hours for its metabolites, compared to Ativan’s half-life of 10-20 hours. However, their onset of actions is almost the same of approximately 1-2 hours after oral administration.  Maximum levels in blood are reached after the intravenuous injection within 15 minutes for Valium and within 10 minutes for Ativan.

Both drugs are efficiently used to relieve symptoms of different anxiety disorders. They are also often used to treat certain types of seizure disorders and to as a sleep inducers. Both medicines can be used as a premedication for inducing anxiolysis, sedation or amnesia before certain medical procedures such as dentistry or endoscopy to reduce anxiety. In addition, Ativan is also used as an adjunct antiemetic in chemotherapy. Because of their anticonvulsant and anxiolytic activities, these medicines are useful for the prevention and treatment of alcohol or opiate withdrawal symptoms. Valium works especially well in such cases.

Both drugs are almost insoluble in water, but diazepam has a better lipid solubility compared to lorazepam. Lorazepam has slow absorption after oral administration and is unsuitable for rectal administration. It is mainly distributed in blood. On the other hand, diazepam, which is well absorbed orally and rectally, because of its high lipid solubility, does not remain too long in the vascular space and quickly redistributes all over the body, particularly to body fat. Diazepam should be better for convulsions treatment as it has much longer elimination half-life time compared to lorazepam. But, lorazepam stays in the vascular space for a longer period of time, making the anticonvulsant effects more durable thus reducing the need for repeated doses. Diazepam anticonvulsant effects last for only 15-30 minutes, but Lorazepam effects last 12-24 hours. So, in the treatment of seizures in epileptic patients, when used intravenuously, Lorazepam is usually considered to be more preferable than Diazepam.  Diazepam effects develop after 6-10 months of therapy, making it a good option for long term maintenance therapy. Diazepam use in emergency cases due to eclampsia is very effective especially when the blood pressure failed to be controlled along with other measures.



 Helps you relax. Valium (Diazepam) is okay for occasional or short-term use (up to 4 weeks) for anxiety and for pain and sleeplessness from muscle spasm. Less severe withdrawal symptoms compared to similar drugs.

 Effective at relieving short-term anxiety and sleeplessness.
Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
Effective at relieving muscle spasms caused by a variety of conditions.
Less severe withdrawal symptoms compared to other benzodiazepines.


 Helps you relax. Ativan (Lorazepam) is okay for occasional or short-term use (up to 4 weeks) for anxiety and sleep. Less likely to have drug interactions, but more likely to cause withdrawal symptoms compared to similar drugs.

Effective at relieving short-term anxiety and sleeplessness.
Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
Less likely to have drug interactions compared to other benzodiazepines, so it might be a better option if you're taking multiple medications.   CLICK BELOW